Diana Bishop, historian and witch, accesses Ashmole 782 and knows she must solve its mysteries. She is offered help by the enigmatic Matthew Clairmont, but hes a vampire and witches should never trust vampires.
In a world where witches, vampires, and daemons live discreetly among humans, Diana Bishop is the last in one long line of distinguished witches. Unwilling to embrace her heritage, she has immersed herself in her career as a historian. Her particular interest is alchemy and she visits Oxford to research some of Elias Ashmoles papers. She requests Ashmole 782 and as soon as she receives it she knows there is something uncanny about it, but when she opens it she is shocked. She learns that 782 has been presumed lost for a very long time and that each species of Creature desires it. She is besieged and threatened and knows that to protect herself, she must uncover all the mysteries of 782. She encounters the enigmatic vampire, Matthew Clairmont, who offers to help her; their mutual attraction is immediate, undeniable and inexplicable because they both know that witches and vampires are not supposed to trust each other. Diana makes her choice and accepts Matthews help. This precipitates them into conflict with the Creature world.
Diana Bishop, scholar and unwilling witch, is studying at the Bodleian Library when she discovers a lost manuscript. Ashmole 782 is wrapped in mystery and invites chaos into Dianas life. Soon she is surrounded by creatures: daemons, witches, and vampires, who all want Ashmole 782 for themselves. Diana finds an unlikely confidant in Matthew Clairmont, a doctor, researcher, and vampire. She is totally unsure, but something says she should trust him, and together the journey starts into the world of All Souls.