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This hour-long dramatic series featured life at St. Eligius Hospital, headed by Drs. Donald Westphall and Daniel Auschlander. Every year, new residents would walk down the halls of St. Eligius; learning to deal with perfectionist Cardiovascular Surgeon Mark Craig was only the beginning of the way the hospital and its interesting patients would change their lives forever.
St. Eligius is an under-funded, decrepit old teaching hospital located in a poor area of 1980s inner city Boston. The physicians, residents, nurses, staff and patients live, work, love, fight, laugh, joke and heal in their own little world, which they jokingly, but lovingly, call "St. Elsewhere."
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		 Ed Begley Jr. 
 Dr. Victor Ehrlich
 
		 Howie Mandel 
 Dr. Wayne Fiscus
 
		 David Morse 
 Dr. Jack Morrison
 
		 Christina Pickles 
 Nurse Helen Rosenthal
 
		 William Daniels 
 Dr. Mark Craig
 
		 Denzel Washington 
 Dr. Philip Chandler
 
		 Norman Lloyd 
 Dr. Daniel Auschlander
 
		 Eric Laneuville 
 Luther Hawkins
 
		 Ed Flanders 
 Dr. Donald Westphall
 
		 Stephen Furst 
 Dr. Elliot Axelrod
 
		 Sagan Lewis 
 Dr. Jacqueline Wade
 
		 Bonnie Bartlett 
 Ellen Craig
 
		 Cynthia Sikes 
 Dr. Annie Cavanero
 
		 Mark Harmon 
 Dr. Robert Caldwell
 
		 Jennifer Savidge 
 Nurse Lucy Papandrao
 
		 Terence Knox 
 Dr. Peter White
 
		 Ellen Bry 
 Nurse Shirley Daniels
 
		 Kavi Raz 
 Dr. Vijay Kochar
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