All hell breaks loose when the Byrnes family meets the Focker family for the first time.
Having managed to enter the longed-for "circle of trust" after the events in , Greg Focker invites the straight-laced Byrnes family to meet mum and dad, the eccentric Fockers. However, as conservative Jack and Dina finally get to meet the uninhibited, cool parents Bernie and Roz, rivalries and secrets emerge, and someone learns a new word. But theres still something fishy about Greg. Will Jack resort to using his infallible contraptions to get to the bottom of Gregs suspicious behaviour?
Having given permission to male nurse Greg Focker to marry his daughter, ex-CIA man Jack Byrnes and his wife travel to Miami to Gregs parents, who this time around are Mr. and Mrs. Focker, who are as different from them as can be. As asked in the first movie, what sort of people name their son Gaylord M. Focker?