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In a coma, Stu Miley a cartoonist who created a comic strip called Monkeybone which features a rascal monkey. He finds himself trapped within his own underground creation and must find a way to get back, while racing against his popular but treacherous character, Monkeybone. Naturally, Monkeybone himself is there, and he and Stu quickly start fighting like cats and dogs. When Stu realizes that his sister, due to a pact they once made, is preparing to pull the plug on him, Stu makes a deal with Hypnos, the god of sleep, to help him steal a golden ticket from Death himself. But when Monkeybone takes over Stus body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever!
Life couldnt be better for cartoonist Stu Miley. He has created a hit comic strip featuring Monkeybone, a petulant rascal with a penchant for wise cracks and racy antics. Stu, happy and in love with his beautiful girlfriend Julie is on the verge of big success, as his comic strip is about to become a national television show. But on the night Stu is to propose to Julie, he is struck down in a freak accident. While Stus body lies comatose - and Julie maintains a constant bedside vigil - his conscious spirit is transported to Downtown, a purgatory-like limbo existing between life and death. Downtown has a carnival landscape populated by mythical gods and creatures who revel in the nightmares of the living. Upon his arrival, Stu learns his ominous fate: Theres no turning back. And just as things seem like they couldnt get any worse, Stus alter ego, Monkeybone, springs to life to stir up some trouble. Now, Stu must outwit Death in order to return to the world of the living before the doctors pull the plug on Stus body. But Monkeybone has hatched his own plot that could thwart Stus plans...
Brendan Fraser
Stu Miley
Bridget Fonda
Julie McElroy
John Turturro
Voice of Monkeybone
Chris Kattan
Organ Donor Stu
Giancarlo Esposito
Hypnos
Rose McGowan
Miss Kitty
David Foley
Herb
Megan Mullally
Kimmy
Bob Odenkirk
Head Surgeon
Pat Kilbane
Burger God Rep
Lisa Zane
Medusa
Whoopi Goldberg
Death
Sandra Thigpen
Alice
Wayne Wilderson
Hutch
Amy Higgins
Clarissa
Alan Gelfant
Dr. Edelstein
Kristin Norton
Nurse
Chris Hogan
Bazoom Toy Rep
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