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United States has just acquired Louisiana from France. An expedition led by Lewis and Clark is sent to survey the territory and go where no white man has gone before. Are they able to overcome the dangers with the help of Sacajawea?
Fred MacMurray
Captain Meriwether Lewis
Charlton Heston
Lt. William Clark
Donna Reed
Sacajawea
Barbara Hale
Julia Hancock
William Demarest
Sgt. Gass
Alan Reed
Charboneau
Eduardo Noriega
Cameahwait
Larry Pennell
Wild Eagle
Argentina Brunetti
Old Crone
Julia Montoya
Crow woman
Ralph Moody
Le Borgne
Herbert Heyes
President Thomas Jefferson
Lester Matthews
Mr. Hancock
Helen Wallace
Mrs. Marsha Hancock
Walter Reed
Cruzatte (helmsman)
Fran Bennett
Undetermined Supporting Role
Joe Canutt
Joe
Frank Fowler
Undetermined Supporting Role
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